VACCELERATE Site Network
491 clinical trial sites have joined the VACCELERATE Site Network so far. The majority is either located in the EU or associated with the H2020 programme.
33 further study sites have expressed interest.
VACCELERATE Site Network laboratories
Become one of our almost 500 registered trial sites and register today!
All you need to do is send an email to email@example.com including:
- Name of your site
- Postal address
- Full name of a contact person
- Contact email address
VACCELERATE and its partners strongly condemn Russia’s attack on Ukraine in violation of international law. The Russian invasion of Ukraine is an indescribable assault on the pillars of our society: freedom, democracy, self-determination and integrity. Our full solidarity goes out to the Ukrainian people.
To express this solidarity, we have decided to deactivate the sites from Belarus and Russia that are represented in the VACCELERATE Site Network. We do not know individual political views and we apologize for the inconvenience. Unfortunately, in this situation we cannot make individual decisions but have to take a clear position. The protection of our values is paramount for us.
We hope that the political situation will change as soon as possible, so that we will be able to reverse this decision.
What is the VACCELERATE Site Network?
The VACCELERATE Site Network is a platform for experienced clinical trial sites interested in conducting COVID-19 vaccine studies. Clinical trial sites register with the network database by answering a short site questionnaire. Any clinical trial site from the European Union and neighbouring countries can register.
The VACCELERATE Site Network is managed by the Clinical Trial Infrastructure of the German Center for Infection Research (DZIF) at the University of Cologne.
What does the Site Network seek to accomplish?
VACCELERATE's site network aims to accelerate clinical development of COVID-19 vaccines for all populations and risk groups. The network database allows for a Europe-wide mapping of experienced clinical trial sites interested in conducting COVID-19 vaccine trials.
The Site Network uses its database to put individual sites in contact with clinical trial sponsors, matching the characteristics of each site with the specific requirements of an individual trial.
It acts as an information broker or matchmaker between interested sites and sponsors, it is not a governing or management body for trial conduct. The network interacts with established research networks but also with clinical trial sites not affiliated with a network.
The network thereby intends to boost the conduct of clinical trials of any scale across country borders in specific populations and risk groups that are not the focus of ongoing phase III trials. There is no upfront limitation on study design: Studies may be head-to-head interventional or observational, on short-term or long-term outcomes, focusing on very small populations or else. Any sponsor from academia, small or medium enterprises (SME), biotech or pharmaceutical industry is welcome to contact the Site Network. In the long term, it is designed to roll out vaccine trials in indications beyond COVID-19.
What information will the Site Network ask for when you register your clinical trial site?
- Name and type of institution, contact details
- Affiliation with infectious disease networks
- Prior clinical trial experience
- Main area of expertise, e.g. disease or indication of interest
- Infrastructure available at your site
- Your preferences for COVID-19 vaccine studies, e.g. specific study populations, inpatient vs. outpatient setting etc.
- You can also share the contacts of other sites you wish to recommend for the Site Network
VACCELERATE Clinical Studies
Clinical trials serve the purpose of clarifying open questions regarding new vaccines, therapies or medicines. By participating in clinical trials, you can make a major contribution to scientific progress. As a study participant you support the research of diseases and the development of new treatment options and at the same time receive comprehensive medical care.
VACCELERATE is carrying out three COVID-19 vaccine trials. The results will be linked here as soon as they are published.
STUDY 1: EU-COVAT-1 AGED
A Multinational, Phase 2, Randomised, Adaptive Protocol to Evaluate Immunogenicity and Reactogenicity of Different COVID-19 Vaccines Administration in Older Adults (≥75) Already Vaccinated Against SARS-CoV-2
Lead: Oliver Cornely, Institution/Sponsor: UHC, Germany
A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network – PubMed (nih.gov)
STUDY 2: EU-COVAT-2 BOOSTAVAC
An International Multicentre, Phase 2, Randomised, Adaptive Protocol to determine the need for, optimal timing of and immunogenicity of administering a booster mRNA vaccination dose against SARS-CoV-2 in the general population (18+ years) already vaccinated against SARS-CoV-2
Lead: Patrick Mallon, Institution/Sponsor: NUID UCD, Ireland
STUDY 3: EU-COVPT-1 COVACC
A Phase 2, Comparative Randomised Trial to Evaluate the Impact of Reduced COVID‐19 mRNA Vaccination Regimen on Immunological Responses and Reactogenicity in Paediatric Subjects with Prior SARS‐CoV‐2 Immunity
Lead: Patricia Bruijning-Verhagen, Institution/Sponsor: UMCU, Netherlands
EudraCT number: 2021-005043-71
COVID-19 Point Prevalence Germany
VACCELERATE Mpox Initiatives
Press Releases and Articles on the VACCELERATE Clinical Studies
Within VACCELERATE we offer several training courses for the VACCELERATE network, organised through our partners and focusing on various topics concerning (vaccine) trial research.
In the VACCELERATE Education Programme, courses have been identified that are suitable for different study team roles. Some of these courses are required in order to participate in VACCELERATE studies and other courses are recommended for further learning if this is of interest to the participant. Which courses are required for participation differs per study team role.
You can find more information on the courses here.
The COVID-NMA initiative – A living mapping and living systematic review of Covid-19 trials
Launched in March 2020, COVID-NMA is an international initiative working in conjunction with the World Health Organization (WHO), led by a team of researchers from Cochrane and other institutions (Université de Paris, Inserm, CNRS, Centre for Evidence-Based Medicine Odense (CEBMO), University of Southern Denmark, Odense University Hospital, Epistemonkos Foundation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan).
The mission is to inform research planning by producing an up-to-date mapping of trial evidence, to inform public health and healthcare decisions by producing relevant, accessible, up-to-date, and trustworthy synthesis of high-quality evidence about the efficacy and safety of interventions for the prevention or treatment of COVID-19 and to improve research value by producing a living monitoring of trial planning, conduct, and reporting and implementing interventions to transform research practices.
For more information: https://covid-nma.com/vaccines/mapping/